Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: KPGLLPSLF KGLRETLSRN LELGLTQGSF AFIHKDFDVK ETFFNLSKRY FDTECVPMNF RNASQAKRLM NHYINKETRG KIPKLFDEIN PETKLILVDY ILFKGKWLTP FDPVFTEVDT FHLDKYKTIK VPMMYGAGKF ASTFDKNFRC HVLKLPYQGN ATMLVVLMEK MGDHLALEDY LTTDLVETWL RNMKTRNMEV FFPKFKLDQK YEMHELLRQM GIRRIFSPFA DLSELSATGR NLQVSRVLQR TVIEVDERGT EAVAGILSEI TAYSMPPVIK VDRPFHFMIY EETSGMLLFL GRVVNPTLL (137-444 aa encoded by BC022261)
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: plasma protein associated with liver regeneration; Protein Z-dependent protease inhibitor; PZ-dependent protease inhibitor; PZI; RASP-1; Regeneration-associated serpin 1; serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; Serpin A10; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; serpin peptidase inhibitor, clade A, member 10
Gene Aliases: PZI; Rasp1; SERPINA10; UNQ707/PRO1358; ZPI
UniProt ID: (Human) Q9UK55, (Rat) Q62975
Entrez Gene ID: (Human) 51156, (Rat) 171154
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