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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.
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Protein Aliases: huntingtin-interacting protein-like protein; protein Solo; SEC14 and spectrin domains 1; unnamed protein product
Gene Aliases: 1500031J16Rik; A930010O20; Solo; Solo/Trio8
UniProt ID: (Human) Q86VW0, (Mouse) Q80UK0
Entrez Gene ID: (Human) 91404, (Mouse) 228071
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