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|Tested species reactivity||Human, Mouse, Primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human SETDB1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15722 targets SETDB1 in IF and WB applications and shows reactivity with Human, mouse, and Non-human primate samples.
The MA5-15722 immunogen is purified recombinant fragment of human SETDB1 expressed in E. Coli.
MA5-15722 detects SETDB1 which has a predicted molecular weight of approximately 180kDa.
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ERG-associated protein with a SET domain, ESET; ERG-associated protein with SET domain; ESET; H3-K9-HMTase 4; H3-K9-HMTase4; histone H3-K9 methyltransferase 4; histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase, H3lysine-9 specific 4; KG1T; KIAA0067; KMT1E; lysine N-methyltransferase 1E; SET domain ERG-associated histone methyltransferase; SET domain, bifurcated 1; SETDB1; tudor domain containing 21
AU022152; ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; mKIAA0067; SETDB1; TDRD21