Search

  • Order Status
  • Quick Order
  • Promos

OriGene

SFRP2 Monoclonal Antibody (OTI6C2), TrueMAB™

View all (19) SFRP2 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Datasheet
Certificates
Protocols
Questions & Answers
Datasheet
Certificates
Protocols
Questions & Answers
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
SFRP2 Monoclonal Antibody (OTI6C2), TrueMAB™

Product Details

CF807497

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

Immunohistochemistry (Paraffin) (IHC (P))

1:150
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OTI6C2

Immunogen

Human recombinant protein fragment corresponding to amino acids 25-295 of human SFRP2 produced in E.coli.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Amount

100 µg

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: FRP 2; MGC128911; MGC153618; MGC53344; SARP 1; SARP-1; SDF 5; secreted apoptosis related protein 1; sFRP 2; sFRP-2; Sfrp2 protein; similar to frizzled-like receptor CRD; testicular tissue protein Li 170; unnamed protein product

View more View less

Gene Aliases: FRP-2; SARP1; SDF-5

View more View less

UniProt ID: (Human) Q96HF1

View more View less

Entrez Gene ID: (Human) 6423

View more View less

Function(s)
fibronectin binding integrin binding enzyme activator activity Wnt-protein binding receptor agonist activity endopeptidase activator activity
Process(es)
regulation of cell growth patterning of blood vessels outflow tract morphogenesis cardiac left ventricle morphogenesis cell-cell signaling response to nutrient positive regulation of cell proliferation negative regulation of cell proliferation response to xenobiotic stimulus negative regulation of gene expression negative regulation of epithelial to mesenchymal transition regulation of neuron projection development regulation of Wnt signaling pathway negative regulation of Wnt signaling pathway positive regulation of cell growth negative regulation of cell growth negative regulation of cell migration positive regulation of cell adhesion mediated by integrin non-canonical Wnt signaling pathway regulation of apoptotic process positive regulation of apoptotic process positive regulation of fat cell differentiation positive regulation of angiogenesis negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter negative regulation of epithelial cell proliferation negative regulation of peptidyl-tyrosine phosphorylation canonical Wnt signaling pathway sclerotome development negative regulation of dermatome development hematopoietic stem cell proliferation cellular response to X-ray negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway negative regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage regulation of midbrain dopaminergic neuron differentiation regulation of stem cell division
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support