The synthetic peptide sequence is 206-237aa, VNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRN
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-D and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 45 ng/mL in healthy individuals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein; COLEC5; collectin 5; Collectin-5; PSAP; PSP-A; PSPA; Pulmonary surfactant-associated protein A; Pulmonary surfactant-associated protein A2; SFTP1; SFTPA; SFTPA2; SFTPA2B; SP-2A beta; SP-2A gamma; SP-A; SP-A2; SP-A2 alpha; SP-A2 delta; surfactant associated protein A; surfactant pulmonary associated protein A1; surfactant, pulmonary-associated protein A1; surfactant, pulmonary-associated protein A2A; Surfactant-associated protein 1 (pulmonary surfactant protein SP-A); Surfactant-associated protein 1 (pulmonary surfactant protein, SP-A)
Gene Aliases: COLEC5; PSAP; PSP-A; PSPA; Sftp-1; SFTP1; SFTPA; Sftpa1; SFTPA2; SFTPA2B; Sftpl; SP-2A; SP-A; SPA2; SPAII