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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 193 and 455 of Human SH3BP5|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30315 targets SH3BP5 in WB applications and shows reactivity with Human samples.
The PA5-30315 immunogen is recombinant fragment corresponding to a region within amino acids 193 and 455 of Human SH3BP5.
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
SAB; SH3 binding protein; SH3 domain-binding protein that preferentially associates with BTK; SH3-domain binding protein 5 (BTK-associated)
SAB; SH3BP-5; SH3BP5