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MA5-15730 targets SLC22A1 in indirect ELISA, FACS and WB applications and shows reactivity with Human samples.
The MA5-15730 immunogen is purified recombinant fragment of human SLC22A1 expressed in E. Coli.
MA5-15730 detects SLC22A1 which has a predicted molecular weight of approximately 61.2kDa.
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
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Protein Aliases: 1-Oct; DKFZp313N1010; FLJ25043; FLJ37489; H oct1_cds; hOCT1; Organic cation transporter 1; solute carrier family 22 (organic cation transporter), member 1; Solute carrier family 22 member 1; SYK
Gene Aliases: HOCT1; OCT1; oct1_cds; SLC22A1
UniProt ID: (Human) O15245
Entrez Gene ID: (Human) 6580
Molecular Function: secondary carrier transporter