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SLC38A1 Antibody (MA5-27605) in ICC/IF
Immunofluorescent analysis of SLC38A1 in human neuroblastoma cell line (SK-N-BE). Sample was fixed with 4% formaldehyde (15 min at RT), incubated with SLC38A1 monoclonal antibody (Product # MA5-27605) using a dilution of 1:100 (1 hour at RT), and followed by Goat Anti-Mouse 488, Phalloidin Texas Red and DAPI secondary antibody at a dilution of 1:100, 1:1000 (60 min at RT) and 1:5000 (5 min at RT). Images are shown as follows: (A) DAPI (blue) nuclear stain, B) Phalloidin Texas Red F-Actin stain, C) SNAT1 Antibody, D) Merged image. Magnifica... View More
Product Details
MA5-27605
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N104/32
Immunogen
Fusion protein amino acids 1-63 of rat SNAT1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2735364
Product Specific Information
1 µg/mL of MA5-27605 was sufficient for detection of SNAT1 in 20 µg of lysates from neocortical neurons cultured under amino acid starvation conditions and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.|Detects approximately 50kDa.
This antibody was formerly sold as clone S104-32.
Target Information
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Amino acid transporter A1; amino acid transporter system A1; Glutamine transporter; MNat2; N-system amino acid transporter 2; rATA1; S38A1; SNAT 1; Sodium-coupled neutral amino acid symporter 1; sodium-coupled neutral amino acid transporter 1; Solute carrier family 38 member 1; solute carrier family 38, member 1; System A amino acid transporter 1; System A transporter 2; System N amino acid transporter 1
Gene Aliases: AA408026; AA409865; AL022800; ATA1; AU015942; GlnT; NAT2; Sa2; SAT1; SLC38A1; SNAT1
UniProt ID: (Human) Q9H2H9, (Rat) Q9JM15, (Mouse) Q8BHI3
Entrez Gene ID: (Human) 81539, (Rat) 170567, (Mouse) 105727
sodium:amino acid symporter activity
L-histidine transmembrane transporter activity
protein binding
amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-amino acid transmembrane transporter activity
L-asparagine transmembrane transporter activity
L-glutamine transmembrane transporter activity
symporter activity
amino acid transporter
neurotransmitter uptake
sodium ion transport
amino acid transport
asparagine transport
glutamine transport
neutral amino acid transport
L-amino acid transport
histidine transport
L-histidine transmembrane transport
amino acid transmembrane transport
cation transmembrane transport
L-alpha-amino acid transmembrane transport
transport
ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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