|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Purified, full length, native, human band 3 protein.|
|Contains||0.1% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
MA1-20211 detects band 3 in human samples. This antibody does not cross react with porcine, mouse, bovine, canine, guinea pig, or equine Band 3.
The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kD protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Defective adaption of erythrocytes during acute hypoxia injury in an elderly population.
MA1-20211 was used in western blot to investigate the influence of age and acute hypoxia on erythrocytes in an aged population
|de Gonzalo-Calvo D,Neitzert K,Fernández M,Vega-Naredo I,Caballero B,García-Macia M,Suárez FM,Rodríguez-Colunga MJ,Solano JJ,Coto-Montes A||The journals of gerontology. Series A, Biological sciences and medical sciences (66:376)||2011|