|Immunohistochemistry (Paraffin) (IHC (P))||1:400-800|
|Western Blot (WB)||Assay Dependent|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Western Blot (WB)||See 5 publications below|
|Immunocytochemistry (ICC)||See 2 publications below|
|Immunohistochemistry (IHC)||See 2 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Rat , Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||A synthetic peptide corresponding to aa625-643 of hNIS protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage conditions||4° C|
MA5-12308 targets Sodium Iodide Symporter in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-12308 immunogen is a synthetic peptide corresponding to aa625-643 of hNIS protein.
Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid. Antibody to NIS showed strong immunostaining in Graves¦ tissues, intermediate staining in papillary and follicular thyroid cancer, and no staining in Hurtle cell cancer or in nonthyroidal tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; Sodium-iodide symporter; Sodium/iodide cotransporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; Solute carrier family 5 member 5
Gene Aliases: NIS; SLC5A5; TDH1
UniProt ID: (Human) Q92911
Entrez Gene ID: (Human) 6528
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