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Invitrogen
SLIRP Recombinant Rabbit Monoclonal Antibody (3H17L4)
FIGURE: 1 / 5
SLIRP Antibody (703632) in ICC/IF
For immunofluorescence analysis, MCF7 cells were fixed and permeabilized for detection of endogenous SLIRP using Anti-Citrate synthase Recombinant Rabbit Monoclonal Antibody (Product # 703632, 1:100 dilution) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of SLIRP protein (green), Panel b) is stained for nuclei (blue) using ProLong™ Diamond Antifade Mountant with D... View More
Product Details
703632
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
3H17L4
Immunogen
Protein corresponding to human SLIRP [aa19- aa103]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2784591
Product Specific Information
This antibody is predicted to react with Monkey, Horse, Cat, Bovine.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
SLIRP (SRA stem-loop interacting RNA binding protein) is expressed in normal and tumor tissues, but the majority of the endogenous SLIRP resides in the mitochondria. SLIRP may regulate mitochondrial functions and has the potential to shut down estrogen in breast cancer cells and testosterone in prostate cancer cells. SLIRP has also been shown to turn down genes involved in energy metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SRA stem-loop-interacting RNA-binding protein, mitochondrial
Gene Aliases: C14orf156; DC23; DC50; PD04872; SLIRP
UniProt ID: (Human) Q9GZT3
Entrez Gene ID: (Human) 81892
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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