This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated. View Details
It is not recommended to aliquot this antibody.
SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Protein Aliases: DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; JV15-2; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; MAD-3; mad3; MGC60396; mMad3; Mothers against decapentaplegic homolog 3; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; SMAD 3; SMAD family member 3; SMAD, mothers against DPP homolog 3; transcription factor
Gene Aliases: AU022421; BOS_10264; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; mad3; MADH3; madh3-A; madh3a; Smad 3; SMAD3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3
Molecular Function: transcription factor