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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Mouse BRM/ SMARCA2 fusion protein derived from within residues 48-214 of the corresponding human sequence|
|Storage buffer||PBS, pH 7.4|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|ChIP assay (ChIP)||Assay-Dependent|
|Immunohistochemistry - Free Floating (IHC (Free))||Assay dependent|
|Immunohistochemistry (PFA fixed) (IHC (PFA))||Assay-Dependent|
|Western Blot (WB)||0.95 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
For Western Blot, this antibody has non-specific bands at 35 kDa and 60 kDa.
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ATP-dependent helicase SMARCA2; BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a, ATP-dependent helicase SMARCA2; BAF190B; BRG1-associated factor 190B; global transcription activator homologous sequence; probable global transcription activator SNF2L2; protein brahma homolog; SNF2-alpha; SNF2/SWI2-like protein 2; subunit of the SWI/SNF chromatin remodeling complex; sucrose nonfermenting 2-like protein 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
2610209L14Rik; BAF190; BAF190B; brahma; BRM; hBRM; hSNF2a; NCBRS; SMARCA2; SNF2; SNF2A; SNF2alpha; SNF2L2; SNF2LA; Sth1p; SWI2