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Product Details
PA5-67318
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SMG1. Recombinant protein control fragment (Product #RP-107960).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2664472
Product Specific Information
Immunogen sequence: QLFSRLNHPEV YVRQSICNLL CRVAQDSPHL ILYPAIVGTI SLSSESQASG NKFSTAIPTL LGNIQGEELL VSECEGGSPP ASQDSNKDEP KS^M
^M
Highest antigen sequence identity to the following orthologs - mouse 98%, rat 25%.
Target Information
This gene encodes a protein involved in nonsense-mediated mRNA decay as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternative spliced transcript variants have been described, but their full-length natures have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSMG-1; Lambda-interacting protein; Lambda/iota protein kinase C-interacting protein; Nonsense mediated mRNA decay-associated PI3K-related kinase SMG1; PI-3-kinase-related kinase SMG-1; Serine/threonine-protein kinase SMG1; SMG-1; smg-1 homolog, phosphatidylinositol 3-kinase-related kinase; SMG1 phosphatidylinositol 3-kinase-related kinase
Gene Aliases: 61E3.4; ATX; KIAA0421; LIP; SMG1
UniProt ID: (Human) Q96Q15
Entrez Gene ID: (Human) 23049
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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