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|Tested species reactivity||Human, Primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human SMN1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15858 targets SMN1 in IF, IHC, and WB applications and shows reactivity with Human and Non-human primate samples.
The MA5-15858 immunogen is purified recombinant fragment of human SMN1 expressed in E. Coli. .
MA5-15858 detects SMN1 which has a predicted molecular weight of approximately 39kDa.
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BCD541, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMN2, SMNT, T-BCD541, component of gems 1; component of gems 1; gemin 1; gemin-1; survival motor neuron 1 protein; survival motor neuron protein; tudor domain containing 16A
BCD541; GEMIN1; SMA; SMA1; SMA2; SMA3; SMA4; SMA@; SMN; SMN1; SMNT; T-BCD541; TDRD16A