|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (DESENSRSPGNKSDN) corresponding to the internal amino acids of SMN1 / SMN2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BCD541; C-BCD541; Component of gems 1; gemin 1; Gemin-1; SMA1; SMA2; SMA3; SMA4; SMN; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1 protein; Survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron 2, centromeric; T-BCD541; tudor domain containing 16A
Gene Aliases: BCD541; GEMIN1; SMA; SMA1; SMA2; SMA3; SMA4; SMA@; SMN; SMN1; SMN2; SMNC; SMNT; T-BCD541; TDRD16A
UniProt ID: (Human) Q16637
Entrez Gene ID: (Human) 6606
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