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Proteintech
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Immunogen sequence: MKPNFSLRL RIFNLNCWGI PYLSKHRADR MRRLGDFLNQ ESFDLALLEE VWSEQDFQYL RQKLSPTYPA AHHFRSGIIG SGLCVFSKHP IQELTQHIYT LNGYPYMIHH GDWFSGKAVG LLVLHLSGMV LNAYVTHLHA EYNRQKDIYL AHRVAQAWEL AQFIHHTSKK ADVVLLCGDL NMHPEDLGCC LLKEWTGLHD AYLETRDFKG SEEGNTMVPK NCYVSQQELK PFPFGVRIDY VLYKAVSGFY ISCKSFETTT GFDPHSGTPL SDHEALMATL FVRHSPPQQN PSSTHGPAER SP
Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lyso-PAF-PLC; Lyso-platelet-activating factor-phospholipase C; N-SMase; Neutral sphingomyelinase; NSMA; Sphingomyelin phosphodiesterase 2; sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Gene Aliases: ISC1; NSMASE; NSMASE1; SMPD2
UniProt ID: (Human) O60906
Entrez Gene ID: (Human) 6610
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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