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FIGURE: 1 / 1
SMUG1 Antibody (CF810367) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SM µg1 (RC212141, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SM µg1. Positive lysates LY415367 (100 µg) and LC415367 (20 µg) can be purchased separately from OriGene.
Product Details
CF810367
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI6B3
Immunogen
Full length human recombinant protein of human SMUG1 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
SMUG1 is a glycosylase that removes uracil from single- and double-stranded DNA in nuclear chromatin, thus contributing to base excision repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC104370; Single-strand selective monofunctional uracil DNA glycosylase; Single-strand selective monofunctional uracil-DNA glycosylase
Gene Aliases: 1200013B09Rik; A930006H09Rik; C85220; FDG; HMUDG; SMUG1; UNG3
UniProt ID: (Human) Q53HV7, (Mouse) Q6P5C5, (Rat) Q811Q1
Entrez Gene ID: (Human) 23583, (Mouse) 71726, (Rat) 315344
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
DNA binding
uracil DNA N-glycosylase activity
protein binding
single-strand selective uracil DNA N-glycosylase activity
DNA N-glycosylase activity
purine-specific mismatch base pair DNA N-glycosylase activity
oxidized base lesion DNA N-glycosylase activity
single-stranded DNA binding
hydrolase activity
hydrolase activity, acting on glycosyl bonds
DNA-3-methylbase glycosylase activity
nicotinamide riboside hydrolase activity
nicotinic acid riboside hydrolase activity
deoxyribonucleoside 5'-monophosphate N-glycosidase activity
DNA metabolism protein
DNA glycosylase
nucleic acid metabolism protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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