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|Tested species reactivity||Bovine, Chicken, Human, Mouse, Primate, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Rat SNAP25 and mouse NS1 Cells.|
|Contains||0.08% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1-5 µg/ml|
|Western Blot (WB)||1-5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control for this product is cerebellum tissue lysate.
SNAP25 (Synaptosomal associated protein of 25 kDa) is a presynaptic plasma membrane protein that is widely distributed throughout the brain and involved in the regulation of neurotransmitter release. Decreased levels of SNAP25 have been found in the brains of patients with Down Syndrome and Alzheimer"e;s Disease (Greber et al.,1999). In addition, a significant reduction in the hippocampal expression of SNAP25 has also been found in patients with Schizophrenia (Fatemi et al., 2001).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
blind drunk; CG17676; CG17884; CG40452; Dmel CG40452; resistance to inhibitors of cholinesterase 4 homolog; SNAP 25; SNAP-25; SNAP25; snp25; SUP; super protein; synaptosomal associated protein-25; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein 25; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa
bA416N4.2; Bdr; BOS_12772; CMS18; dJ1068F16.2; GENA70; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SNAP-25a; SNAP-25B; SNAP25; sp; SUP