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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15420 targets SND1/P100 in WB applications and shows reactivity with Human samples.
The MA5-15420 immunogen is purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli.
MA5-15420 detects SND1/P100 which has a predicted molecular weight of approximately 102kDa.
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
100 kDa coactivator; EBNA-2 co-activator (100kD); EBNA2 coactivator p100; p100 co-activator; p100 EBNA2 co-activator; SND1; SND1-BRAF fusion; staphylococcal nuclease domain containing 1; Staphylococcal nuclease domain-containing protein 1; TDRD11; testis tissue sperm-binding protein Li 82P; Tudor domain-containing protein 11; Tudor-SN; TudorSN
p100; SND1; TDRD11