|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 162 and 345 of Human SNF5|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29844 targets SNF5 in WB applications and shows reactivity with Human samples.
The PA5-29844 immunogen is recombinant protein fragment corresponding to a region within amino acids 162 and 345 of Human SNF5.
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.
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Nucleoside, nucleotide and nucleic acid metabolism DNA metabolism mRNA transcription mRNA transcription regulation Developmental processes Other developmental process Cell cycle Cell cycle control Cell proliferation and differentiation