Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: RRRYREFVWL RQRLQSNALL VQLPELPSKN LFFNMNNRQH VDQRRQGLED FLRKVLQNAL LLSDSSLHLF LQSHLNSEDI EACVSGQTKY SVEEAIHKFA LMNRRFPEED EEGKKENDID YDSESSSSGL GHSSDDSSSH GCKVNTAPQE
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sorting nexin-10
Gene Aliases: OPTB8; SNX10
UniProt ID: (Human) Q9Y5X0
Entrez Gene ID: (Human) 29887
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