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Positive Control: 293T, A431, HeLa, HepG2
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SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.
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Protein Aliases: methamphetamine-responsive transcript 1; RP11-98D18.12-005; Sorting nexin-27
Gene Aliases: KIAA0488; MRT1; MY014; SNX27
UniProt ID: (Human) Q96L92
Entrez Gene ID: (Human) 81609
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