This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
MA1-105 detects SOD1 in human and mouse samples and has been successfully used in Western blot, immunohistochemistry, immunocytochemistry and immunofluorescence applications.
SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ALS1; Cu(2+)-Zn2+ superoxide dismutase; Cu/Zn superoxide dismutase; epididymis secretory protein Li 44; homodimer; hSod1; indophenoloxidase A; IPOA; SOD; SOD, soluble; Superoxide dismutase 1; Superoxide dismutase [Cu-Zn]; superoxide dismutase, cystolic
Gene Aliases: ALS; ALS1; B430204E11Rik; Cu/Zn-SOD; CuZnSOD; HEL-S-44; homodimer; hSod1; Ipo-1; Ipo1; IPOA; SOD; Sod-1; SOD1; SODC
Molecular Function: oxidoreductase