MA5-17177 targets SOX9 in ICC, IF and WB applications and shows reactivity with Human samples.
The MA5-17177 immunogen is purified recombinant fragment of human SOX9 expressed in E. Coli.
MA5-17177 detects SOX9 which has a predicted molecular weight of approximately 56kDa.
The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
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Protein Aliases: SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY box 9; SRY-related HMG-box, gene 9; Transcription factor SOX-9
Gene Aliases: CMD1; CMPD1; SOX9; SRA1; SRXX2; SRXY10
UniProt ID: (Human) P48436
Entrez Gene ID: (Human) 6662