|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||18 amino acid peptide near the amino terminus of human SPINSTER|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A recommended positive control is human placenta tissue lysate.
At least four isoforms of SPINSTER are known to exist. This antibody is not expected to cross-react with other members of the spinster family of proteins.
SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily. SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death. The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.