Immunogen sequence: WAHTSSPGTIL SSISLGESTF LTINLLATAG KVAGCEWGGE GRFTRSEAPK LAASAKRLCF LRFLTNKWGG M
Highest antigen sequence identity to the following orthologs - mouse 25%, rat 27%.
Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. May play a role in signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: androgen down regulated in mouse prostate; likely ortholog of androgen down regulated gene expressed in mouse prostate; Protein ADMP; Serine palmitoyltransferase small subunit B; serine palmitoyltransferase, small subunit B; Small subunit of serine palmitoyltransferase B; ssSPTb
Gene Aliases: ADMP; C3orf57; SPTSSB; SSSPTB
UniProt ID: (Human) Q8NFR3
Entrez Gene ID: (Human) 165679