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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GRPTASVIPS GVEWIKARVT ELNPDKNCIH TDDDEKISYR YLIIALGIQL DYEKIKGLPE GFAHPKIGSN YSVKTVEKTW KALQDFKEGN AIFTFPNTPV KCAGAPQKIM YLSEAYFRKT GKRSKANIIF NTSLGAIFGV KKYADALQEI IQERNLTVNY KKNLIEVRAD KQEAVFENLD KPGETQVISY EMLHVTPPMS PPDVLKTSPV ADAAGWVDVD KETLQHRRYP NVFGIGDCTN LPTSKTAAAV AAQSGILDRT ISVIMKNQTP TKKYDGYTSC PLVTGYNRVI LAEFDYKAEP LETFPFDQSK ERLSMYLMKA DLMPFLYWNM MLRGYWGGPA FLRKLFHLGM S
SQRDL (Sulfide: quinone oxidoreductase, mitochondrial) catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Although the SQRDL precursor protein displays a molecular weight of 50 kDa, a prominent band at about 46 kDa is detected by western blot. This discrepancy reflects the cleavage of an N-terminal targeting sequence of 4 kDa during the import of the protein into the mitochondria. SQRDL is one of the enzymes involved in H2S signaling in a discrete population of neurons, oligodendrocytes, and endothelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: sulfide dehydrogenase like; sulfide quinone reductase-like; unnamed protein product
Gene Aliases: CGI-44; PRO1975; SQR; SQRDL
UniProt ID: (Human) Q9Y6N5
Entrez Gene ID: (Human) 58472
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