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|Tested species reactivity||Human, Xenopus|
|Published species reactivity||Rat, Human, Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Mass-isolated nuclei from Xenopus Laevis oocytes.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
SR proteins appear to be recruited from nuclear "speckles", in which they are concentrated, to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Human||1:1000||The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B.||Anderson ES,Lin CH,Xiao X,Stoilov P,Burge CB,Black DL||RNA (New York, N.Y.) (18:1041)||2012|
|Mouse||Not Cited||RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon.||Buratti E,Muro AF,Giombi M,Gherbassi D,Iaconcig A,Baralle FE||Molecular and cellular biology (24:1387)||2004|
|Rat||Not Cited||RNA splicing capability of live neuronal dendrites.||Glanzer J,Miyashiro KY,Sul JY,Barrett L,Belt B,Haydon P,Eberwine J||Proceedings of the National Academy of Sciences of the United States of America (102:16859)||2005|
||RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon.||Buratti E,Muro AF,Giombi M,Gherbassi D,Iaconcig A,Baralle FE||Molecular and cellular biology (24:1387)||2004|
arginine/serine-rich 3; pre-mRNA splicing factor SRp20; pre-mRNA-splicing factor SRP20; SFRS3; Splicing factor; splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich, 20-kD; SRP20
SFRS3; SRP20; SRSF3