Immunogen sequence: EEMEKESGPG QKRPNKQEES ESPVERPLKE NPPNKMTQEK LEESSTIGQD QTLMERDTEG GAAEINCNGV IEVINYTQNS NNETLRHKED LHNANDCDVQ NLNQESSFLS SQNGDSSTSQ ETDSCTPITS EVSDTMVCQS SSTVGQSFSE QHISQLQESI RAEIPCEDEQ EQEHNGPLDN KGKSTAGNFL V; Positive Samples: 293T, HepG2, MCF7, HeLa, THP-1 ; Cellular Location: Cytoplasm, Microsome, Microsome, Nucleus, Nucleus matrix
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Serine/arginine-rich protein-specific kinase 1; serine/arginine-rich splicing factor kinase 1; serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SR protein-specific kinase 1; SR-protein-specific kinase 1; SRPK1; SRSF protein kinase 1
Gene Aliases: AU017960; SFRSK1; SRPK1