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Product Details
TA500618
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4A11
Immunogen
Full-length protein expressed in 293T cell transfected with human SSX2 expression vector
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 5.2; cancer/testis antigen family 5, member 2a; CT5.2; MGC119055; MGC15364; MGC3884; Protein SSX2; sarcoma, synovial, X-chromosome-related 2; Synovial sarcoma, X breakpoint 2; synovial sarcoma, X breakpoint 2B; Tumor antigen HOM-MEL-40
Gene Aliases: CT5.2; CT5.2A; HD21; HOM-MEL-40; SSX; SSX2; SSX2A; SSX2B
UniProt ID: (Human) Q16385
Entrez Gene ID: (Human) 6757
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