This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
This antibody is predicted to react with Monkey, Dog, Sheep
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
STAG2 is a component of the cohesin complex. This complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cohesin subunit SA-2; SA2; SCC3 homolog 2; Stromal antigen 2
Gene Aliases: bA517O1.1; SA-2; SA2; SCC3B; STAG2
UniProt ID: (Human) Q8N3U4
Entrez Gene ID: (Human) 10735