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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Armenian hamster / IgG1|
|Immunogen||Recombinant full length protein (Mouse).|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Gel Shift (GS)||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent.|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-21890 detects STAT4 in Human and Mouse samples.
MA1-21890 has been successfully used in Gel Shift, Immunoprecipitation and Western Blot procedures.
MA1-21890 immunogen corresponds to recombinant full length protein (Mouse).
The STAT 4 protein is a transcription factor activated by hormone and cytokines. STAT 4 is most similar to STAT 1 (52%) and STAT 3 (47%). Functionally, STAT 4 is similar to other STAT family members in that it can be tyrosine phosphorylated by JAK 1 or JAK 2. STAT 4 forms homodimers and heterodimers with related STAT family members. Tyrosine phosphorylated STAT 4 can bind the interferon g activated site (GAS), and serine phosphorylation is also required for maximal transcriptional activity. STAT 4 expression is restricted to the thymus, spleen, and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.