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Invitrogen
STS Recombinant Rabbit Monoclonal Antibody (PSH05-74)
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STS Antibody (MA5-56384) in IHC (P)
Immunohistochemical analysis of Steroid Sulfatase was performed using formalin-fixed paraffin-embedded human placenta tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 1... View More
Product Details
MA5-56384
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PSH05-74
Immunogen
Recombinant protein within Human Steroid sulfatase aa 22-184 and aa 235-583.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3668613
Product Specific Information
Positive Control: Jurkat cell lysate HepG2 cell lysate, MCF7 cell lysate, Huh7 cell lysate, T-47D cell lysate, human placenta tissue.
Tissue Specificity: Expressed in placenta and 180 other cell types or tissues.
Subcellular Location: Cytoplasmic vesicle. Endoplasmic reticulum.
Sequence Similarities: No Cross with Mouse/Rat.
Predicted band size: 65 kDa.
Target Information
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Arylsulfatase C; ASC; Estrone sulfatase; Steroid sulfatase; Steryl-sulfatase; Steryl-sulfate sulfohydrolase
Gene Aliases: ARSC; ARSC1; ASC; ES; SSDD; STS; XLI
UniProt ID: (Human) P08842
Entrez Gene ID: (Human) 412
glycosphingolipid metabolic process
steroid catabolic process
female pregnancy
learning or memory
positive regulation of cell proliferation
epidermis development
response to pH
response to organic cyclic compound
response to peptide hormone
skin development
response to estrogen
post-translational protein modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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