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Product Details
TA811076
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Mouse / IgG2b |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI3A5 |
Immunogen |
Full length human recombinant protein of human STX3 produced in HEK293T cell. |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 1% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Target Information
The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: syntaxin 3A; Syntaxin-3
Gene Aliases: STX3; STX3A; Syn-3
UniProt ID: (Human) Q13277, (Mouse) Q64704, (Rat) Q08849
Entrez Gene ID: (Human) 6809, (Mouse) 20908, (Rat) 81802
Molecular Function:
SNARE protein
intracellular protein transport
positive regulation of cell proliferation
synaptic vesicle docking
neuron projection development
synaptic vesicle fusion to presynaptic active zone membrane
positive regulation of cell adhesion
vesicle docking
positive regulation of chemotaxis
long-term synaptic potentiation
positive regulation of protein localization to plasma membrane
positive regulation of protein localization to cell surface
transport
neurotransmitter transport
exocytosis
vesicle-mediated transport
membrane fusion
intracellular transport
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