Immunogen sequence: GVGGDPAQLA QRISSNIQKI TQCSVEIQRT LNQLGTPQDS PELRQQLQQK QQYTNQLAKE TDKYIKEFGS LPTTPSEQRQ RKIQKDRLVA EFTTSLTNFQ KVQRQAAERE KEFVARVRAS SRVSGSFPED SSKERNLVSW ESQTQPQV
ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.
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Protein Aliases: Syntaxin-7
Gene Aliases: STX7
UniProt ID: (Human) O15400
Entrez Gene ID: (Human) 8417