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|Tested species reactivity||Fruit fly, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 37-66 amino acids from the C-terminal region of human Drosophila SUMO|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CG4494-PA; GAP modifying protein 1; LD07775p; sentrin; Smt3; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; ubiquitin-homology domain protein PIC1; ubiquitin-like protein SMT3C; ubiquitin-like protein UBL1
DAP1; GMP1; OFC10; OK/SW-cl.43; PIC1; SENP2; SMT3; SMT3C; SMT3H3; SUMO1; UBL1