MA5-15732 targets SUZ12 in IF and WB applications and shows reactivity with Human samples.
The MA5-15732 immunogen is purified recombinant fragment of human SUZ12 expressed in E. Coli.
MA5-15732 detects SUZ12 which has a predicted molecular weight of approximately 83.1kDa.
This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
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Protein Aliases: ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; JJAZ1; Joined to JAZF1 protein; KIAA0160; Polycomb protein SUZ12; Suppressor of zeste 12 protein homolog; SUZ12
Gene Aliases: CHET9; JJAZ1; KIAA0160; SUZ12
UniProt ID: (Human) Q15022
Entrez Gene ID: (Human) 23512
Molecular Function: nucleic acid binding