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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50 - 1:100 | - |
Immunocytochemistry (ICC/IF) |
1:50 - 1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 37-200 of human SYT11. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
4.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808772 |
Immunogen sequence: WSCCHQQAEK KQKNPPYKFI HMLKGISIYP ETLSNKKKII KVRRDKDGPG REGGRRNLLV DAAEAGLLSR DKDPRGPSSG SCIDQLPIKM DYGEELRSPI TSLTPGESKT TSPSSPEEDV MLGSLTFSVD YNFPKKALVV TIQEAHGLPV MDDQTQGSDP YIKM; Positive Samples: U-251MG, Mouse brain, Rat brain; Cellular Location: Cell junction, Cytoplasmic vesicle, Membrane, Single-pass membrane protein, secretory vesicle, synapse, synaptic vesicle membrane
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: synaptotagmin 11; synaptotagmin 12; Synaptotagmin XI; Synaptotagmin-11; SytXI
Gene Aliases: 1500004A13Rik; 3632445O20Rik; 5430404N14Rik; 6530420C11Rik; AI851970; KIAA0080; SYT11; SYT12; sytXI
UniProt ID: (Human) Q9BT88, (Mouse) Q9R0N3, (Rat) O08835
Entrez Gene ID: (Human) 23208, (Mouse) 229521, (Rat) 60568
Molecular Function:
membrane trafficking regulatory protein
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