Immunogen sequence: WSCCHQQAEK KQKNPPYKFI HMLKGISIYP ETLSNKKKII KVRRDKDGPG REGGRRNLLV DAAEAGLLSR DKDPRGPSSG SCIDQLPIKM DYGEELRSPI TSLTPGESKT TSPSSPEEDV MLGSLTFSVD YNFPKKALVV TIQEAHGLPV MDDQTQGSDP YIKM; Positive Samples: U-251MG, Mouse brain, Rat brain; Cellular Location: Cell junction, Cytoplasmic vesicle, Membrane, Single-pass membrane protein, secretory vesicle, synapse, synaptic vesicle membrane
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010].
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Protein Aliases: synaptotagmin 11; synaptotagmin 12; Synaptotagmin XI; Synaptotagmin-11; SytXI
Gene Aliases: 1500004A13Rik; 3632445O20Rik; 5430404N14Rik; 6530420C11Rik; AI851970; KIAA0080; SYT11; SYT12; sytXI