This target displays homology in the following species: Cow: 83%; Dog: 92%; Guinea Pig: 93%; Horse: 83%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 92%
Sarcalumenin is a 160 kDa acidic calcium binding glycoprotein found to reside at the inner membrane of the sarcoplasmic reticulum in a calcium dependent manner. The gene encoding sarcalumenin also encodes an alternate splice variant, a 53 kDa glycoprotein which co-localizes with sarcalumenin. These two proteins are found in the longitudinal sarcoplasmic reticulum and the nonjunctional membranes of the terminal cisternae. They have been observed to co-localize with calcium-ATPase suggesting that they are involved in calcium transport and sequestration.
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Protein Aliases: Sarcalumenin; sarcolumenin; sarcoplasmic reticulum glycoprotein; SRL
Gene Aliases: 9830004M20Rik; AW108387; Sar; SRL