Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Immunohistochemistry (IHC) |
- | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:25-1:50 | - |
Immunocytochemistry (ICC/IF) |
- | View 2 publications 2 publications |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Dog, Human |
Host/Isotype |
Mouse / IgM |
Class |
Monoclonal |
Type |
Antibody |
Clone |
5C5 |
Immunogen |
Purified rabbit striated muscle allactin. |
Conjugate |
Unconjugated |
Form |
Liquid |
Storage buffer |
ascites |
Contains |
0.09% sodium azide |
Storage conditions |
4° C, do not freeze |
RRID |
AB_557425 |
MA1-21597 detects alpha sarcomeric actin in bovine, guinea pig,human, rabbit, rat, fish, pig, snake, Xenopus and sheep samples.
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: act; actg; Actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Alpha-actin-1; Alpha-actin-2; Alpha-cardiac actin; alpha-sma; beta-actin; Cell growth-inhibiting gene 46 protein; dfna20; dfna26; MGC75587; nemaline myopathy type 3
Gene Aliases: AAT6; ACTA; ACTA1; ACTA2; ACTC; ACTC1; ACTSA; ACTVS; ASD5; ASMA; CFTD; CFTD1; CFTDM; CMD1R; CMH11; GIG46; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; SHPM
UniProt ID: (Human) P68133, (Human) P62736, (Human) P68032
Entrez Gene ID: (Human) 58, (Human) 59, (Human) 70
Molecular Function:
actin and actin related protein
actin or actin-binding cytoskeletal protein
cytoskeletal protein
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