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|Tested species reactivity||Bovine, Ferret, Hamster, Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A peptide containing residues 496-509 from mouse SR-BI plus an N-terminal cysteine was coupled to KLH. CSPAAKGTVLQEAKL-COOH.|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris citrate, pH 7-8|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:400|
|Immunohistochemistry (IHC)||2.5-5 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||Assay-Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||2.5-5 µg/ml|
|Western Blot (WB)||1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: mouse liver lysate or protein.
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor-like 1); CD36 antigen-like 1; CLA-1; Collagen type I receptor, thrombospondin receptor-like 1; HDL QTL 1; SCARB1; scavanger receptor class B type 1; Scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; Scavenger Receptor-B1; Scavenger Receptor-BI; SR-B1; SR-BI; SRB1
AI120173; BOS_16485; CD36; CD36L1; CLA-1; CLA1; D5Ertd460e; Hdlq1; HDLQTL6; Hlb398; mSR-BI; SCARB1; SR-B1; SR-BI; SRB1; SRBI