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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 50 and 274 of Human Serine palmitoyltransferase 2|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31130 targets Serine palmitoyltransferase 2 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-31130 immunogen is recombinant fragment corresponding to a region within amino acids 50 and 274 of Human Serine palmitoyltransferase 2.
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
hLCB2a; HSN1C; LCB 2; LCB2; LCB2A; long chain base biosynthesis protein 2; long chain base biosynthesis protein 2a; NSAN1C; serine palmitoyltransferase; serine palmitoyltransferase 2; serine palmitoyltransferase, long chain base subunit 2; serine palmitoyltransferase, subunit II; serine-palmitoyl-CoA transferase 2; SPT 2; SPT2; subunit II
AI173915; hLCB2a; HSN1C; KIAA0526; LCB2; LCB2A; mKIAA0526; NSAN1C; SPT2; SPTLC2