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|Tested species reactivity||Human|
|Published species reactivity||Rat, Fruit fly, Human, Not Applicable|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||5-Hydroxytryptamine hydrochloride (3-(2-aminoethyl)-5-hydroxyindole;serotonin)|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:20-1:40|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-12111 targets Serotonin in IHC (P) applications and shows reactivity with Human samples.
The MA5-12111 immunogen is 5-Hydroxytryptamine hydrochloride (3-(2-aminoethyl)-5-hydroxyindole;serotonin).
Serotonin-positive cells are present in gastric, duodenal, jejunal, ileal, colonic, and appendiceal mucosae. Positive cells are sparse and usually occur in the lower half of the gastric and intestinal mucosae. In the appendix, in addition to the mucosal serotonin-containing cells, there are single or small clusters of serotonin-positive cells in the sub-epithelial region of the lamina propria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Serotonergic neurons of the Drosophila air-puff-stimulated flight circuit.
MA5-12111 was used in immunohistochemistry to study serotonergic neurons during air-puff-stimulated flight
|Sadaf S,Hasan G||Journal of biosciences (39:575)||2014|
Synaptic activity in serotonergic neurons is required for air-puff stimulated flight in Drosophila melanogaster.
MA5-12111 was used in immunohistochemistry to study Drosophila melanogaster air-puff-stimulated flight and the modulatory role of serotonergic neuron synaptic activity
|Sadaf S,Birman S,Hasan G||PloS one (7:null)||2012|
Inositol 1,4,5-trisphosphate receptor and dSTIM function in Drosophila insulin-producing neurons regulates systemic intracellular calcium homeostasis and flight.
MA5-12111 was used in immunohistochemistry to study the role of calcium signaling in homeostasis and flight
|Agrawal N,Venkiteswaran G,Sadaf S,Padmanabhan N,Banerjee S,Hasan G||The Journal of neuroscience : the official journal of the Society for Neuroscience (30:1301)||2010|
The effects of chronic administration of sumatriptan and dipyrone on serotonergic system in the rat brain: an immunohistochemical study.
MA5-12111 was used in immunohistochemistry to study the effect of chronic administration of sumatriptan and dipyrone on the rat brain serotonergic system
|Genç E,Avunduk MC,Genç BO,Sahin AS,Oz M||Acta neurologica Scandinavica (120:264)||2009|
|Not Applicable||Not Cited||
Well-differentiated endocrine tumor of the distal common bile duct: a case study and literature review.
MA5-12111 was used in immunohistochemistry to examine a clinical case of differentiated endocrine tumor of the distal common bile duct
|Nesi G,Lombardi A,Batignani G,Ficari F,Rubio CA,Tonelli F||Virchows Archiv : an international journal of pathology (449:104)||2006|
Hypoxia signature of splice forms of tryptophanyl-tRNA synthetase marks pancreatic cancer cells with distinct metastatic abilities.
MA5-12111 was used in immunocytochemistry to evaluate the hypoxia-induced alternative splicing of tryptophanyl-tRNA synthetase in pancreatic cancer cells
|Paley EL,Paley DE,Merkulova-Rainon T,Subbarayan PR||Pancreas (40:1043)||2011|