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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated, corresponding to the C-terminal portion of human Serotonin Receptor 7.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay dependent|
|Immunofluorescence (IF)||13 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-24575 detects 5-HT7 Receptor in human samples.
PA1-24575 has been successfully used in immunocytochemistry procedures.
The PA1-24575 immunogen is a synthetic peptide, KLH conjugated, corresponding to the C-terminal portion of human Serotonin Receptor 7. Sequence identity/similarity to Mouse: 0/0%. Rat: 0/0%.
5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autistism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa. 5-HT7 Receptor has been reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel. An EST has been isolated from a testis library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
5-HT-7; 5-HT-X; 5-HT7; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled