PA1-28361 detects serum Amyloid P from human samples.
PA1-28361 has been successfully used in immunofluorescence, ELISA, immunoelectrophoresis, immunohistochemistry, and radioimmunodiffusion applications.
The PA1-28361 immunogen is: Purified human SAP component
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 9.5S alpha-1-glycoprotein; epididymis secretory sperm binding protein Li 92n; MGC88159; pentaxin-related; pentraxin-2; pentraxin-related; PTX2; SAP; Serum amyloid P-component; Serum amyloid P-component(1-203)
Gene Aliases: APCS; HEL-S-92n; PTX2; SAP
UniProt ID: (Human) P02743
Entrez Gene ID: (Human) 325