Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.
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Protein Aliases: Apcs; APCS amyloid P-component serum protein; Ptx2; SAP; Serum amyloid P-component
Gene Aliases: Apcs; Ptx2; Sap
UniProt ID: (Mouse) P12246
Entrez Gene ID: (Mouse) 20219