Recommended positive controls: 293T, A431.
Predicted reactivity: Mouse (89%), Rat (92%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Seryl-tRNA synthetase (SerRS) catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 220.127.116.11; serine tRNA ligase 1, cytoplasmic; Serine--tRNA ligase, cytoplasmic; SerRS; Seryl-tRNA synthetase; seryl-tRNA synthetase, cytoplasmic; Seryl-tRNA(Ser/Sec) synthetase
Gene Aliases: SARS; SERRS; SERS
UniProt ID: (Human) P49591
Entrez Gene ID: (Human) 6301