|Tested species reactivity||C. elegans|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Full-length recombinant Sir2.1 protein.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200-1:500|
|Western Blot (WB)||1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
Sir2 (silent information regulator 2) protein plays a crucial role in regulating the life span of C. elegans by means of caloric restricion. Overexpression of the protein can extend the life span, and is, thus, a regulator of longevity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Brief Communication: SIR-2.1-dependent lifespan extension of Caenorhabditis elegans by oxyresveratrol and resveratrol.
PA1-16933 was used in western blot to study the lifespan extension of Caenorhabditis elegans by resveratrol and oxyresveratrol by SIR-2.1-dependence
|Lee J,Kwon G,Park J,Kim JK,Lim YH||Experimental biology and medicine (Maywood, N.J.) (241:1757)||2016|