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|Tested species reactivity||Human|
|Published species reactivity||Rat, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide from N-terminus of human alpha smooth muscle isoform of actin|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.6, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine, chicken, amphibian, mouse, porcine, rabbit and rat based on sequence homology.
A suggested positive control is small intestine (smooth muscle) or leiomyosarcoma.
This antibody stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained. It reacts with tumors arising from smooth muscles and myoepithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Novel assessment of haemodynamic kinetics with acute exercise in a rat model of pulmonary arterial hypertension.
PA1-37024 was used in immunohistochemistry - paraffin section to study the effect of exercise on already-elevated pulmonary arterial pressures and right ventricular wall stress in a rat model of pulmonary arterial hypertension
|Brown MB,Chingombe TJ,Zinn AB,Reddy JG,Novack RA,Cooney SA,Fisher AJ,Presson RG,Lahm T,Petrache I||Experimental physiology (100:742)||2015|
Altered vascular microenvironment by bevacizumab in diabetic fibrovascular membrane.
PA1-37024 was used in immunohistochemistry to study the effect of bevacizumab on vascular endothelial cells, pericytes and myofibroblasts of fibrovascular membranes in diabetic retinopathy
|Nakao S,Ishikawa K,Yoshida S,Kohno R,Miyazaki M,Enaida H,Kono T,Ishibashi T||Retina (Philadelphia, Pa.) (33:957)||2013|
AAT6; ACTSA; alpha-cardiac actin; alpha-sma; cell growth-inhibiting gene 46 protein
AAT6; ACTA2; ACTSA; ACTVS; GIG46; MYMY5